Allyl-isothiocyanate-AITC-生命科学试剂-MCE.pdf

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Inhibitors•ScreeningLibraries•Proteins

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Allylisothiocyanate

Cat.No.:HY-B1515

CASNo.:57-06-7

Synonyms:AITC;3-Isothiocyanatoprop-1-ene

分⼦式:C₄H₅NS

分⼦量:99.15

作⽤靶点:EndogenousMetabolite;Bacterial;Apoptosis;Autophagy;

Glycosidase

作⽤通路:MetabolicEnzyme/Protease;Anti-infection;Apoptosis;

Autophagy

储存⽅式:Pureform-20°C3years

Insolvent-80°C6months

-20°C1month

BIOLOGICALACTIVITY

⽣物活性Allylisothiocyanate(AITC)存在于许多常见的⼗字花科蔬菜中。Allylisothiocyanate具有抗菌活性，是⼀种有

效的杀菌剂(bactericidal)。Allylisothiocyanate会导致细菌代谢物泄漏，并显著增加β-半乳糖苷酶(β-

galactosidase)的活性。Allylisothiocyanate具有抗癌活性，可诱导癌细胞凋亡(apoptosis)和⾃噬(

autophagy)。

IC50TargetHumanEndogenousMetabolite

REFERENCES

[1].LinCM,etal.Antibacterialmechanismofallylisothiocyanate.JFoodProt.2000Jun;63(6):727-34.

[2].TararA,etal.AnticancerActivity,Mechanism,andDeliveryofAllylIsothiocyanate.Bioengineering(Basel).2022Sep14;9(9):470.

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