Thiethylperazine-dimaleate-Standard-生命科学试剂-MCE.pdfVIP

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Thiethylperazinedimaleate(Standard)

Cat.No.:HY-B1794AR

CASNo.:1179-69-7

分⼦式:C₃₀H₃₇N₃O₈S₂

分⼦量:631.76

作⽤靶点:DopamineReceptor;HistamineReceptor;Bacterial;Amyloid-β

作⽤通路:GPCR/GProtein;NeuronalSignaling;

Immunology/Inflammation;Anti-infection

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性Thiethylperazine(dimaleate)(Standard)是Thiethylperazine(dimaleate)的分析标准品。本产品⽤于研究及

分析应⽤。Thiethylperazinedimaleate是⼀种吩噻嗪衍⽣物，是⼀种⼝服有效的多巴胺D2受体和组胺H1受

体拮抗剂。Thiethylperazinedimaleate也是⼀种选择性的ABCC1激活剂，可减少⼩⿏中的淀粉样β(Aβ)负

荷。Thiethylp

IC50TargetDopamineD2-receptor[1]

HistamineH1-receptor[1]

ABCC1[2]

Enterococcusfaecalis[3]

REFERENCES

[1].CzeizelAE,etal.Case-controlstudyofteratogenicpotentialofthiethylperazine,ananti-emeticdrug.BJOG.2003May;110(5):497-9.

[2].KrohnM,etal.Cerebralamyloid-βproteostasisisregu