药理学第26章H1受体阻滞剂习题.pdfVIP

PharmacologySection26

一、A1

1.Amongthefollowingdrugs,theH1receptorblockerwiththestro

ngestcentralinhibitoryeffectis

A.Tripelamine

B.Pro

methazineC.

C

h

lorphenira

mineD.

LoratadineE.

Meclozine

2.Loratadinebelongsto

A.AntibioticsB.

AntineosticdrugsC.

AntiallergicdrugsD.

Sedative-hypnoticsE.

Nonsteroidal

anti-infltory

drugs

3.WhichofthefollowingarenotclinicalapplicationsofH1

receptorblockers?

A.InsomniaB.Motion

sicknessC.

AnaphylacticshockD.

AllergicdiseaseE.

Vomitingcausedby

drugs

4.Whichofthefollowinghasweakcentralfunctionandalmostnocentral

sedativeeffect?

A.

Di

phenhydramine

B.

C

hlorpheniramine

C.Pyridoxamine

D.AstemizoleE.

Promethazine

5.Themechanismbywhichcimetidineinhibitsgastricacid

secretionis

A.BlockMreceptor

B.BlockHrece

1

ptorC.BlockH2

receptorD.Blockα

receptorE.Blockβ

receptor

6.WhatiswrongwiththevariousdescriptionsofH1

receptorblockingdrugs?

A.MainlyusedtotreatallergicdiseasesB.The

mainrepresentativedrugisfamotidineC.Can

beusedtotreatvomitingofpregnancyD.Can

beusedtotreatallergicinsomniaE.Themost

commonadversereactioniscentraldepression.

7.Whatiswrongwith

promethazine?

A.ItisanHreceptorblocking

1

drug.B.Ithasobviouscentral

inhibitoryeffect.

C、能抑制胃酸分泌

D、有抗过敏作用

E、有止吐作用

8、下列药物不是H1受体拮抗剂的是

A、阿司咪唑

B、苯海拉明

C、氯苯那敏

D、氯丙嗪

E、异丙嗪

9、下列中枢抑制作用最强的药物是

A、氯苯那敏

B、苯海拉明

C、阿司咪唑

D、吡苄明

E、氯雷他定

10、苯海拉明不具有的性质是

A、

B、

C、抗胆碱

D、镇吐

E、降低肾素分泌

11、无明显中枢副作用的H1受体阻断药是

A、苯海拉明

B、异丙嗪

C、吡苄明

D、氯苯那敏

E、阿司咪唑

12、H1受体阻断剂药理作用是

A、能与组胺竞争H1受体，拮抗组胺作用

B、和组胺起化学反应，使组胺失效

C、有相反的药理作用，发挥生理对抗效应

D、能稳定肥大细胞膜，抑制组胺的释放

E、拮抗ACh作用

二、B

1、A.组胺

B.西咪替丁

C.