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- 2025-11-06 发布于浙江
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CNScircuitscandirectlysenseglucoseandspecificfattyacids,integratingthisinformationtomodulatecaloricintake(1,22).ThisfindingsexpandtheknowledgeoftheseCNSsensingmechanismstoincludeaproteincomponent:theaminoacidL-leucine.(D)ProposedmodelfortheroleofmTORsignalinginthehypothalamicregulationofenergybalance.Anorecticsignals,suchasaminoacids(L-leucine),leptin,andre-feeding,increasehypothalamicmTORsignaling.IncreasedmTORactivityleadstoadecreaseinfoodintake.RapamycininhibitshypothalamicmTOR,causinganincreaseinfoodintak
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