冠心病合并甲亢患者使用碘克沙醇1例并文献分析.pdfVIP

·138·中国现代药物应用2024年2月第18卷第3期ChinJModDrugAppl,Feb2024,Vol.18,No.3

·案例分析·

冠心病合并甲亢患者使用碘克沙醇1例并文献分析

张新琼戴喜钦

【摘要】为了探讨冠心病合并甲状腺功能亢进(甲亢)患者选用何种碘对比剂,本研究依据1例冠

心病合并甲亢患者病情特点,临床药师检索及查阅文献,阐述碘对比剂对冠心病合并甲亢风险人群甲状

腺功能影响及防治措施。冠心病合并甲亢患者行经皮冠状动脉介入术时优先选择第3代等渗非离子型

对比剂如碘克沙醇,在碘对比剂前立即给予预防性治疗(甲巯咪唑片30mg,po,qd,持续14d)。临床中

应关注碘对比剂对甲状腺功能影响,使用前需筛查高风险人群,并综合评估患者甲状腺疾病、心血管合

并症、年龄等因素后,个体化给予药物预防。

【关键词】冠心病；碘对比剂；甲状腺功能亢进；经皮冠状动脉介入术

DOI：10.14164/11-5581/r.2024.03.037

Acasestudyonthetreatmentofcoronaryheartdiseasecombinedwithhyperthyroidismusingiodixanol

andliteratureanalysisZHANGXin-qiong,DAIXi-qin.DepartmentofPharmacy,GuangzhouXinhaiHospital,

Guangzhou510300,China

【Abstract】Inordertoexplorewhichiodinecontrastagentsshouldbeusedinpatientswithcoronary

heartdiseasecomplicatedwithhyperthyroidism.Basedonthecharacteristicsofapatientwithcoronaryheart

diseasecomplicatedwithhyperthyroidism,thisstudydescribedtheeffectsofiodine-containingcontrastagents

onthyroidfunctioninpatientsatriskofcoronaryheartdiseasecomplicatedwithhyperthyroidismandtheir

preventivemeasuresthroughclinicalpharmacistssearchandliteraturereview.Thethirdgenerationisotonic

nonioniccontrastagentsuchasioxanolispreferredduringpercutaneouscoronaryinterventioninpatientswith

coronaryheartdiseaseandhyperthyroidism,andprophylactictreatment(thiamazoletablets,30mg,po,qd,for14d)

wasgivenimmediatelybeforeiodine-containingcontrastagent.Inclinicalpractice,attentionshouldbepaidto

theimpactofiodine-containingcontrastagentsonthyroidfunction.Beforeuse,high-riskpopulationsshouldbe

screened,andpersonalizedmedicationshouldbegivenaftercomprehensiveevaluationoffactorssuchasthyroid

disease,cardio