2A-2B-Dengue-protease-substrate-生命科学试剂-MCE.pdfVIP

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2A/2BDengueproteasesubstrate

Cat.No.:HY-P11420

CASNo.:410532-55-7

分⼦式:C₃₉H₆₈N₁₆O₁₁

分⼦量:937.06

Sequence:{Ac}-Arg-Thr-Ser-Lys-Lys-Arg-{pNA}

SequenceShortening:{Ac}-RTSKKR-{pNA}

作⽤靶点:DengueVirus

作⽤通路:Anti-infection

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性2A/2BDengueproteasesubstrate(Ac-RTSKKR-pNA)是DengueNS2B-NS3蛋⽩酶的⼀种肽底物。2A/2B

Dengueproteasesubstrate⽤于DengueNS2B-NS3蛋⽩酶底物肽选择性抑制剂的开发[1]。

REFERENCES

[1].LeungD,etal.Activityofrecombinantdengue2virusNS3proteaseinthepresenceofatruncatedNS2Bco-factor,smallpeptide

substrates,andinhibitors.JBiolChem.2001Dec7;276(49):45762-71.

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