第四届中医药高质量发展大会成功召开,发布《中医药+人工智能乌镇共识》.pdfVIP

第卷第期天津中医药大学学报

444Ｖｏｌ．44Ｎｏ．4

年月

２０254ＪｏｕｒｎａｌｏｆＴｉａｎｊｉｎＵｎｉｖｅｒｓｉｔｙｏｆＴｒａｄｉｔｉｏｎａｌＣｈｉｎｅｓｅＭｅｄｉｃｉｎｅApr.2０25

EvaluationofthepharmacologicaleffectofYiqiQingfeiGranulesinterventionon

chronicfatiguesyndromemodelmice

1111111

GAOPanwei，XUXingdi，LUOZijuan，CHANGHuilin，WANGNa，LUXingyue，YUANQing，

23111

DINGHui，ZHANGXiaoguang，ZHANGHan，MIAOLin，CHAILijuan

（1.InstituteofTraditionalChineseMedicine，TianjinUniversityofTraditionalChineseMedicine，Tianjin301617，

China；2.CollegeofPharmaceuticalEngineering，TianjinUniversityofTraditionalChineseMedicine，Tianjin

301617，China；3.TianjinZhongyiPharmaceuticalCo.Ltd.，Tianjin301617，China）

Abstract：[Objective]Toexploretheanti鄄fatigueeffectofYiqiQingfeiGranules（YQQF）onchronicfatiguemodel

mice.[Methods]Malebalb/cmicewererandomlydividedintothecontrolgroup，themodelgroup，YQQFlowdose

group（2.4g/kg），YQQFmiddledosegroup（4.8g/kg），YQQFhighdosegroup（9.6g/kg）.Miceinthecontrolandmodel

groupsweregivensaline，andothermiceweregivenYQQF.Onehourafterintragastricadministration，allmice

exceptthoseinthecontrolgroupweresubjectedtoswimmingtrainingfor2hours，andtheprocesslastedfor6weeks.

Allmicewerekilled24hoursafterthelastexhaustiveswimmingtraining.Forcedswimmingtestandrotarodtestwere

carriedouttoevaluateendurance.Contentsofglycogenandadenosinetriphosphate（ATP），