7-tert-Butoxy-7-oxoheptanoic-acid-生命科学试剂-MCE.pdfVIP

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Inhibitors•ScreeningLibraries•Proteins

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7-(tert-Butoxy)-7-oxoheptanoicacid

Cat.No.:HY-W108876

CASNo.:1469894-57-2

分⼦式:C₁₁H₂₀O₄

分⼦量:216.28

作⽤靶点:PROTACLinkers

作⽤通路:PROTAC

储存⽅式:Pureform-20°C3years

4°C2years

Insolvent-80°C6months

-20°C1month

BIOLOGICALACTIVITY

⽣物活性7-(tert-Butoxy)-7-oxoheptanoicacid是⼀种PROTAClinker，可⽤于合成PROTAC分⼦。

体外研究PROTACscontaintwodifferentligandsconnectedbyalinker;oneisaligandforanE444ubiquitinligase

andtheotherisforthetargetprotein.PROTACsexploittheintracellularubiquitin-proteasomesystemto

selectivelydegradetargetproteins.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

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