AM-2394-Standard-生命科学试剂-MCE.pdfVIP

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Inhibitors•ScreeningLibraries•Proteins

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AM-2394(Standard)

Cat.No.:HY-100221R

CASNo.:1442684-77-6

分⼦式:C₂₂H₂₅N₅O₄

分⼦量:423.47

作⽤靶点:Glucokinase;ReferenceStandards

作⽤通路:MetabolicEnzyme/Protease;Others

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性AM-2394(Standard)是AM-2394(HY-100221)的分析标准品。本产品⽤于研究及分析应⽤。AM-2394是⼀种

新型的glucokinase激活剂(GKA)。AM-2394激活葡萄糖激酶(GK),EC50为60nM。

IC50TargetEC50:60nM(glucokinase)[1]

REFERENCES

[1].DransfieldPJ,etal.NovelSeriesofPotentGlucokinaseActivatorsLeadingtotheDiscoveryofAM-2394.ACSMedChemLett.2016

May23;7(7):714-8.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

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