D-myo-Inositol-1-4-5-6-tetraphosphate-tetrasodium-Inositol-1-4-5-6-tetraphosphate-tetrasodium-生命科学试剂-MCE.pdfVIP

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D-myo-Inositol-1,4,5,6-tetraphosphatetetrasodium

Cat.No.:HY-W703190A

Synonyms:Inositol1,4,5,6-tetraphosphatetetrasodium;D-Ins(1,4,5,6)P4

tetrasodium

分⼦式:C₆H₁₂Na₄O₁₈P₄

分⼦量:588

作⽤靶点:ChlorideChannel;DrugIsomer

作⽤通路:MembraneTransporter/IonChannel;Others

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性D-myo-Inositol-1,4,5,6-tetraphosphatetetrasodium(D-Ins(1,4,5,6)P4tetrasodium)是肌醇寡聚磷酸的异构

体之⼀。在8-10μM时，它⼏乎完全抑制钙激活的氯离⼦通道。

REFERENCES

[1].YangX,etal.Inositol1,3,4-trisphosphateactsinvivoasaspecificregulatorofcellularsignalingbyinositol3,4,5,6-tetrakisphosphate.J

BiolChem.1999Jul2;274(27):18973-80.

[2].XieW,etal.Inositol3,4,5,6-tetrakisphosphateinhibitsthecalmodulin-dependentproteinkinaseII-activatedchlorideconductanceinT84

colonicepithelialcells.JBiolChem.1996Jun14;271(24):14092-7.

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Caution:Producthasnotbeenfullyvalidatedformedicalapplications.