Ethyl-4-4-4-5-5-tetramethyl-1-3-2-dioxaborolan-2-yl-butanoate-生命科学试剂-MCE.pdfVIP

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Inhibitors•ScreeningLibraries•Proteins

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Ethyl4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)butanoate

Cat.No.:HY-W613030

CASNo.:1392140-97-4

分⼦式:C₁₂H₂₃BO₄

分⼦量:242.12

作⽤靶点:PROTACLinkers

作⽤通路:PROTAC

储存⽅式:Pureform-20°C3years

Insolvent-80°C6months

-20°C1month

BIOLOGICALACTIVITY

⽣物活性Ethyl4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)butanoate是⼀种PROTAClinker，可⽤于合成

PROTAC分⼦。

体外研究PROTACscontaintwodifferentligandsconnectedbyalinker;oneisaligandforanE626ubiquitinligase

andtheotherisforthetargetprotein.PROTACsexploittheintracellularubiquitin-proteasomesystemto

selectivelydegradetargetproteins.

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Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

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