Ethyl-4-piperazin-1-yl-benzoate-生命科学试剂-MCE.pdfVIP

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Inhibitors•ScreeningLibraries•Proteins

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Ethyl4-(piperazin-1-yl)benzoate

Cat.No.:HY-77779

CASNo.:80518-57-6

分⼦式:C₁₃H₁₈N₂O₂

分⼦量:234.3

作⽤靶点:PROTACLinkers

作⽤通路:PROTAC

储存⽅式:Powder-20°C3years

4°C2years

Insolvent-80°C6months

-20°C1month

BIOLOGICALACTIVITY

⽣物活性Ethyl4-(piperazin-1-yl)benzoate是⼀种PROTAClinker，可⽤于合成PROTAC分⼦。

体外研究PROTACscontaintwodifferentligandsconnectedbyalinker;oneisaligandforanE627ubiquitinligase

andtheotherisforthetargetprotein.PROTACsexploittheintracellularubiquitin-proteasomesystemto

selectivelydegradetargetproteins.

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Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

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