Ethyl-3-bromopropanoate-生命科学试剂-MCE.pdfVIP

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Inhibitors•ScreeningLibraries•Proteins

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Ethyl3-bromopropanoate

Cat.No.:HY-W007449

CASNo.:539-74-2

分⼦式:C₅H₉BrO₂

分⼦量:181.03

作⽤靶点:PROTACLinkers

作⽤通路:PROTAC

储存⽅式:Storeatroomtemperature3years

*Insolvent:-80°C,6months;-20°C,1month(Storeatroom

temperature3years)

BIOLOGICALACTIVITY

⽣物活性Ethyl3-bromopropanoate是⼀种PROTAClinker，可⽤于合成PROTAC分⼦。

体外研究PROTACscontaintwodifferentligandsconnectedbyalinker;oneisaligandforanE624ubiquitinligase

andtheotherisforthetargetprotein.PROTACsexploittheintracellularubiquitin-proteasomesystemto

selectivelydegradetargetproteins.

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Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

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