Giffonin-P-生命科学试剂-MCE.pdfVIP

Hotline:400-820-3792

Inhibitors•ScreeningLibraries•Proteins

www.MedChemE

GiffoninP

Cat.No.:HY-N9821

CASNo.:1830306-93-8

分⼦式:C₁₉H₂₂O₇

分⼦量:362.37

作⽤靶点:Glycosidase

作⽤通路:MetabolicEnzyme/Protease

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性GiffoninP是⼀种靶向α-葡萄糖苷酶(α-glucosidase)的选择性抑制剂，IC50为55.3μM。GiffoninP可延缓

碳⽔化合物⽔解和葡萄糖吸收，发挥抗⾼⾎糖活性。GiffoninP可降低餐后⾎糖⽔平，主要应⽤于2型糖尿病

的研究。

REFERENCES

[1].MasulloM,etal.Corylusavellana:ASourceofDiarylheptanoidsWithα-GlucosidaseInhibitoryActivityEvaluatedbyinvitroandinsilico

Studies.FrontPlantSci.2022Feb14;13:805660.

[2].MasulloM,etal.GiffoninsJ-P,HighlyHydroxylatedCyclizedDiarylheptanoidsfromtheLeavesofCorylusavellanaCultivarTondadi

Giffoni.JNatProd.2015Dec24;78(12):2975-82.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

Tel:400-820-3792;021Fax:021E-mail:tech@MedC