艾昆纬-现代化肥胖试验：eCOA和设备集成的最佳实践-2026 .pdfVIP

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ModernizingObesityTrials:

BestPracticesforeCOA

andDeviceIntegration

Tableofcontents

Introduction1

Background2

Obesity:Ahighlypatient-centrictherapeuticarea2

Measuringtheintangible:HoweCOAdrivesclinicaltrialoutcomesinobesitytrials3

Fromdevicestoinsights:Theroleofdigitalhealthtechnologies4

ThepowerofeCOAanddeviceintegration:Makingtrialsmorepatient-centric4

Recommendationsforintegration5

Introduction

Obesityisacomplexglobalhealthchallenge,broadinscaleyetdeeplypersonal

inimpact.Efectiveclinicaltrialsforobesitydrugsmustcapturemorethanweight

orBMI.Theymustincorporatereal-time,patient-centereddataonbehavior,

motivation,emotionalwell-beinganddailyfunction.TheintegrationofDigital

HealthTechnologies(DHTs),speciicallyelectronicClinicalOutcomeAssessments

(eCOA)andconnectedmedicaldevices,meetsthisneed,markingatransformative

shiftinhowobesityclinicaltrialsaredesigned,executedandexperienced.

ThisoutcomesresearchguideexplorestherolesofeCOAandconnecteddevices

inobesitytrialsandexplainshowtheirintegrationdrivesmoreaccurate,higher-

qualityclinicaltrialoutcomes.Thisguidealsohighlightsthesharedbeneits

forstakeholdersandprovidespracticalrecommendationsforapproaching

integrationandensuringseamlessexecutionacrossglobalobesitystudies.

IQVIAhasbeeninvolvedinthemajorityofobesitytrialsconductedinthepast

iveyearsandhassupporteddrugapprovalsforthreemajorobesitydrugs.