LCK-degrader-3-生命科学试剂-MCE.docxVIP

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Inhibitors?ScreeningLibraries?Proteins

www.MedChemE

LCKdegrader-3

Cat.No.:HY-180928

CASNo.:3095032-59-7

分?式:C??H??N?O?

分?量:430.46

作?靶点:MolecularGlues;Src;LigandsforE3Ligase

作?通路:PROTAC;ProteinTyrosineKinase/RTK

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性LCKdegrader-3(Compound20)

?种于CRBN的LCK分?胶(Molecularglue)降解剂。LCKdegrader-3

可?于急性淋巴细胞??病研究[1]。

IC50TargetLckCereblon

REFERENCES

[1].HuM,etal.Direct-to-BiologyEnabledMolecularGlueDiscovery.JAmChemS