阜外FFR原理及临床应用.pptVIP

病变≠缺血冠脉病变的解剖和功能学评价FractionalFlowReserve,FFR

FractionalFlowReserve-FFR

定义和公式假设FFR被定义为狭窄存在和正常时心肌最大血流量（QS，QN）的比值（Pa－Pv）（Pd－Pv）QN＝,QS＝RRFFR=QS/QN=（Pd-Pv）/（Pa-Pv）≈Pd/Pa

FFR的临界值FFR0.75提示狭窄有功能意义的特异性100%FFR0.80提示狭窄无功能意义的敏感性90%需要测量FFR~65%~20%

DEFERSTUDY

CardiacDeathAndAcuteMIAfter5Years 3.37.915.705101520%P=0.20P0.03P0.005DEFERPERFORMREFERENCEFFR0.75FFR0.75PijlsNHJ,etal.JAmColl