24章+利尿药和脱水药5.pptVIP

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  • 约5.83千字
  • 约 78页
  • 2026-09-08 发布于重庆
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ADH(orvassopressin)regulatingthewaterreabsorptioninthecollectingductbyAQPwaterchannels.waterreabsorptionbythecollectingductisunderhormonalcontrolofvassopressin.WaterPermeabilityisprimarilyregulatedbyacAMPdependentvesiculartraffickingmechanism.VassopressinbindstoV2receptorofthecollectingductcellthattheninitiatesaseriesofcellulareventsinvolvingcAMPThePKA-mediatedproteinphosphorylationtriggeredanincreasedrateofaquaporin-2(AQP2)-containingvesicleintotheapicalmembraneandthenumberofAQP2waterchannels

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