勃起功能障碍治疗进展.pptVIP

血管活性药物应用的反指征镰刀细胞贫血白血病抗凝治疗HIV或肝炎等传染病有阴茎异常勃起病史*性腺功能低下症的病因促性腺激素低下性腺功能低下症药物垂体肿瘤先天性疾病Pradet-willi综合症*磷酸二酯酶5抑制剂治疗男性勃起功能障碍的机理*cGMPspecificproteinkinaseNOGuanylylcyclaseGTPcGMPK+Ca2+DecreasedCa2+Smoothmusclerelaxation5GMPPDE5PDE5InhibitorCavernousnerveEndothelialcellNOL-ArginineOxygenNonadrenergicNoncholinergicSexualStimulationSmoothmusclecell*三种磷酸二酯酶5抑制剂的分子结构式SildenafilVardenafiltadalafilNHNNOOCH3OOHHNHNNNCH3OSNNOOCH3CH3NHNNNCH3OOCH3SNNCH3OOCH3OCH3*Sildenafil,vardenafilandtada