抗肾小球基底膜(GBM)病.pptVIP

Allele-1Allele-2Dr2LODscoreDRB1*1501DQB1*06020.5620.30551.22DRB1*1501DRB1*090110.03910.41DRB1*1501DQB1*03030.8170.0244.44DRB1*1501DQA1*05020.2430.0011.03DQB1*0602DRB1*09010.6850.0182.81DQB1*0602DQB1*030310.0358.55DQB1*0602DQA1*05020.460.0050.82DQB1*0303DRB1*09010.6410.38556.05DQB1*0303DQA1*050210.0010.47DQA1*0502DRB1*09010.14800*LOD3:Confirmedlinkage.LOD-2:Nolinkage.LOD=0:thepossibilityisequalLinkageanalysisamongthesignificantallelesUnpublisheddata抗GBM病的科学问题病因易感性诱发因素：环境?病因表型差异*病因遗传易感背景自身免疫T细胞B细胞