核磁医学Pharmaron PHN603医师培训课件PPT Lecture 04.pdfVIP

PracticalOrganicChemistry

Carrying

out

reactions

BeforetheReaction

•Do

you

have

the

procedure

to

follow

•Do

you

have

the

system

(TLC,

LCMS)

to

monitor

•Do

you

know

the

safety

feature

of

the

reaction,

by

product

etc

CONFIDENTIALPage2

RulesofThumb

•Planning

–When

a

reaction

is

new

to

you,

one

millimole

is

often

a

good

starting

point,

if

reactant

is

not

limiting.

If

reactant

is

precious,

it

can

be

divided

into

three

or