白内障围手术期用药分析.doc

白内障围手术期用药分析 赵语1 聂绩 2（1. 重庆医科大学附属第一医院药剂科 重庆 400016；2. 重庆医科大学药学院 重庆 400016） [摘要] 目的：了解白内障手术患者在围手术期使用抗菌药物和其它辅助药物的现状及合理性，以期为临床医师的白内障围手术期用药提供参考,促进合理用药。方法：随机抽取2007年4月1日至2008年3月31日重庆医科大学附属第一医院（重医大附一院）的白内障手术病历60份，进行回顾性调查和分析。结果：白内障围手术期用药包括抗菌药物（全身和局部使用）和辅助用药（促凝血药，降低眼内压药物，抗炎药和中成药等）。其中全身使用抗菌药物均为预防用药，使用率100%，使用频率最高的是阿莫西林舒巴坦注射剂。局部使用抗菌药物有氨基糖苷类，喹诺酮类，四环素类和林可霉素类，使用频率最高的是妥布霉素和庆大霉素。结论：重医大附一院白内障围手术期用药总体上较为合理，但在预防使用抗菌药物的药品选择，用药剂量，用药时间等方面的合理性有待提高。 [关键词] 用药分析；围手术期；白内障；抗菌药物 [中图分类号]R969.3 〔文献标识码〕A 〔文章编号〕 Analysis of drug use on patients with cataracta in perioperative period ZHAO Yu 1, NIE Ji 2 (1. Department of Pharmacy, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China；2 Pharmacy College, Chongqing Medical University, Chongqing 400016，China) ABSTRACT: OBJECTIVE To investigate status quo and rationality of the use of antibacterials and other drugs on patients with cataracta in perioperative period. METHODS The data obtained randomly from clinical records of 60 operative patients with cataracta in the First Affiliated Hospital of Chongqing Medical University from April 1, 2007 to March 31, 2008 were analyzed retrospectively. RESULTS The drugs used during cataracta perioperative period consisted of antibacterials and other drugs. All the patients were treated with systematic antibacterials for prevention of infection. Among the antibacterials amoxicillin and sulbactam was frequently used. The antibiotics for topical ophthalmic use consisted of aminoglycosides, quinolones,tetracyclines and lincosamides. Tobramycin and gentamycin were frequently used among the antibacterials in local application. CONCLUSIONS The use of antibiotics and other drugs on patients with cataracta in perioperative period is rationality in the hospital. However, the antibiotics category, dose and administration time for prophylactic use during cataracta perioperative period should be improved. KEY WORDS: analysis of drug use；surgical procedures；cataracta；antibacterials 白内障