气雾剂药物在机械通气中的递药Tongji Lung protective ventilation.pptx

Aerosol Drug DeliveryDuringMechanical Ventilation;Our goals for today …..;Scope of this topic;Nebulizers vs MDIs;Scope of this topic;Fundamental Principles;Settings for aerosol delivery;Outcome Measures;Technical Issues;Factors influencing aerosol delivery*;;How do we measureaerosol delivery ?;Fundamental terminology;;;;;;;;;;;;;;;;;Study Conclusion 研究结论;;;;;Particle Size 颗粒大小;Bias Flow 偏流;Brand of Nebulizer 雾化器的牌子;Results (drug delivery) 结果（药物运输）;Results (in vivo data);Vibrating Mesh Technology 震动网丝技术;Vibrating Mesh Technology;Vibrating Mesh Technology;;;;;What did we learn?;Bias flow reduces aerosol delivery. 偏流减少雾化效果 Particle size may be difficult to manage. 微粒大小很难控制 Little standardization exists, even today. 直到今天还没有规范标准 Untested modifications and approaches may or may not be effective. Bench testing is important. 未测试的方法可能也不可能有效，Bench法很重要;Take home message