癌症患者化疗辅助用药临床应用情况分析.pdfVIP

中国药物应用与监测 2010年4月第7卷第2期 Chinese Journal of Drug Application and Monitoring, Vol.7, No.2, April 2010 癌症患者化疗辅助用药临床应用情况分析 王伟兰，朱 曼，郭代红，刘皈阳（解放军总医院药品保障中心，北京100853 ） [摘要] 目的：对我院肿瘤大楼化疗辅助药物的使用情况进行分析。方法：采用药库计算机信息管理系统收集2008 年2 – 8 月 肿瘤大楼化疗辅助药物的有关数据，并进行统计分析。化疗辅助用药包括：保肝药、抑酸药、止吐药、升白细胞药、扶正祛邪 中成药、生物免疫调节剂。结果：用药金额位居首位的是扶正祛邪中成药，为522.07 万元，占用药总金额的31.16% ，其他排 序依次为保肝药占18.69%、止吐药占14.77%、生物免疫调节剂占14.45%、升白细胞药占10.62%、抑酸药占10.30%。还原型 谷胱甘肽钠、多烯磷脂酰胆碱注射液、硫普罗宁片和奥美拉唑钠分别居DDDs 前4 位。结论：化疗辅助用药对提高机体免疫 力，降低抗肿瘤药物的毒性，保证化疗顺利进行具有重要意义。 [关键词] 癌症；化疗；辅助用药；合理用药 [ 中图分类号] R969.3 [ 文献标识码] A [ 文章编号] 1672 – 8157(2010)02 – 0095 – 02 Application analysis of adjuvant drugs in cancer chemotherapy WANG Wei-lan, ZHU Man, GUO Dai-hong, LIU Gui-yang(Pharmaceutical Care of PLA General Hospital, Beijing 100853, China) [ABSTRACT] Objective: To investigate the utilization of adjuvant drugs in cancer chemotherapy in our hospital. Methods: The data retrieved from computer information management system of drug storeroom were analyzed statistically regarding the utilization of adjuvant drugs in chemotherapy from February to August 2008 ．Adjuvant drugs included hepatoprotectives, acid- suppressing drugs, antiemetics, interleukin drugs, Chinese patent drugs and bio-immunomodulator. Results: Chinese patent drugs for strengthening healthy energy to eliminate evils dominated the first in terms of consumption sum, which was 5.220 7 million yuan, consumption sum of Chinese patent drugs occupied 31.16% of the total consumption sum, followed by hepatoprotectives (18.69%), antiemetic (14.77%), bio-immunomodulator (14.45%), interleukin drug (10.62%) and acid-suppressing drugs (10.30%). Glutathione sodium for injection, polyene phosphatidylcholine for injection, tiopronin tablets, omeprazole sodium placed the top 4 in terms of DDDs. Conclusion: The adjuvant drugs in chemotherapy showed important significance in improving the body immunity, decreasing the toxicity of