武汉大学病毒学2006-2007学年度第二学期期末考试B卷.docVIP

武汉大学生命科学学院 2006-2007学年度第二学期期末考试 《病毒学》试卷 姓名 学号 专业 得分 Are the following statements true or false? （ ）1. Ribosomal frameshifting allows viruses to produce a polyprotein from an mRNA. （ ）2. Ribosomal frameshifting allows viruses to produce varying amounts of different proteins from an mRNA. （ ）3. Suppression of termination codons allows some viruses to produce multiple proteins from a polycistronic mRNA. （ ）4. Viruses with non-segmented minus-sense genomes produce monocistronic mRNAs. （ ）5. Viruses with minus-sense genomes always contain a virus-specific transcriptase/replicase within the virus nucleocapsid. （ ）6. Viruses with non-segmented miuns-sense genomes are translated to produce a single long polyprotein. （ ）7. Retrovirused are the only RNA viruses whose genomes are transcribed by cellular RNA polymersase. （ ）8. Hepadnavirus and Caulimovirus genomes contain a number of overlapping reading frames. （ ）9. Treatment of virus infections with drugs is cost effective compared with vaccination. （ ）10. Any of the stages of virus replication can be potential target for antiviral chemotherapy. （ ）11. The majority of antiviral drugs in use are nucleoside/nucleotide analogues. （ ）12. Ribavirin is only active against influenza virus. （ ）13. Viruses may become resistant t antiviral drugs. （ ）14. Subunit vaccines are generally the most effective and least expensive virus vaccines. （ ）15. The hepatitis B virus vaccine currently in use is produced by genetic engineering. （ ）16. Inactivated virus vaccines are sometimes not as effective as live virus vaccines because they fail to stimulate mucosal and cell-mediated immunity. （ ）17. The majority of successful virus vaccines are currently based on attenuated viruses. （ ）18. Retroviruses have been successfully used as vectors for gene therapy. （ ）19. Most disease states are multi-factorial. （ ）20. Inflammation, fever, headaches and skin rashes are frequently not caused by vir