论文TiCl4促进的磺酰胺与醚的N-烷基化反应.docVIP

  TiCl4-Mediated Direct N-Alkylation of Sulfonamides with Inactive Ethers# 5 10 15 20 25 30 35 40 Chen Jiayan, Zeng Wei** (School of Chemistry and Chemical Engineering, South China University of Techology, Guangzhou 510641) Abstract: N-alkylsulfonamides is a class of biologically active compounds such as antibacterial, anticancer, antiviral functions, and many classical N-alkylsulfonamides synthetic methods which involved sulfonyl halides with amines, sulfonamide with alcohol were reported successively. In this paper, TiCl4–mediated intermolecular or intramolecular direct N-alkylation rea