e05.Blood and Hemopoiesis血液淋巴和血发生.pptVIP

组织胚胎学课件 七年制英文医学班专用 Chapter 5 Blood and Hemopoiesis 1.?????? Components: ---formed elements: 45% red blood cell-erythrocyte white blood cell-leukocyte platelets ---plasma: 55%, PH 7.3-7.4, 90% water contain: plasma protein(albumin, globulin, fibrinogen), lipidprotein, enzymes, hormone, vitamin, inorganic salt and products of metabolism *serum: is plasma in which the fibrinogen has been removed by clotting 1.???Cells 1) erythrocyte, red blood cell ---normal number: (4.2-5.5)X1012/L in male (3.5-5.0)X1012/L in female ---structure: biconcave discs in shape, 7.5-8.5 um in diameter, 1-2um thick no nucleus and organella filled with hemoglobin, Hb: about 1/3 -normal number: 120-150g/L in male 105-135g/L in female -combine and transfer O2 and CO2 erythrocyte membrane skeleton: -change shape -main component is spectrin and actin blood type antigen: A, B : -membrane protein -ABO blood type -hemolysis→erythrocyte ghost *anemia: RBC 3.0X1012 /L or Hb 100g/L * reticulocyte: 0.5-1% of total erythrocyte population or 3-6% in naonate immature cell remained ribosome-delicate network structure when stained with brilliant cresyl blue will disappear after 1-3 days ---life span: 120 days 2) leukocyte ---a group of large cells with nucleus ---involve in defense and immune reaction ---normal number: (4.0-10) X109/L ---classification: granulocytes: /neutrophil /eosinophil /basophil agranulocytes: /lympocyte /monocyte ①???? neutrophil: ---normal percentage: 50-70% of total leukocyte population ---structure: LM: round, 10-12um in diameter rob-liked or poly morphous nucleus, 2-5 lobes fine neutrophilic granules-pink cytoplasm EM: specific granule: 80% small, 0.3-0.4 u