肿瘤干细胞的调控机制及其临床意义.docVIP

肿瘤干细胞的调控机制及其临床意义 王旗春，田艳萍 Regulatory mechanism of cancer stem cells and their clinical significance Wang Qi-chun, Tian Yan-ping Abstract: Cancer stem cells are a small number of cells with the nature of stem cells in tumor tissue, their self-renewal and differentiation are under strict control. Cancer stem cells are the cause of tumor formation, recurrence and metastasis. At present, there are various researches of regulatory and control mechanisms of the cancer stem cells, including abnormal signal transduction, aneuploidy in the nucleus, the proto-oncogene activation and inactivation of tumo