侧柏叶药理作用研究进展论文.docVIP

侧柏叶药理作用研究进展 [摘 要] 综合叙述了侧柏叶的化学成分、药理作用的研究进展。侧柏叶化学成分有挥发油、黄酮类化合物、鞣 [关键词] 侧柏叶;挥发油;双黄酮; 鞣;防脱发 Oriental Arborvitae Pharmacological Research YuYue (Department of Biology, East China Institute of Technology, Fuzhou, Jiangxi 344000) 【Abstract】 neral description of the chemical composition of Biota orientalis, pharmacological research progress. Oriental Arborvitae chemical composition of volatile oil, flavonoids, tannins and resins, vitamin C and so on. Therefore its leaves have antibacterial, anti-tumor, anti-red blood cell oxidation, hemostasis, blood pressure and protecting myocardial ischemia reperfusion injury, antitussive, expectorant, asthma, and sedation and so on. In view of the main body of contemporary society - people, hair loss is serious, causes of hair loss, hair loss prevention and aspects of P. orientalis in the study, found that anti-hair loss, especially in Biota orientalis has a unique effect. Preparation of shampoo but still faces some difficulties, but also needs further study and learn from the advanced herbal liquid extraction and preparation technology for greatly improved. 【Keywords】 Biota orientalis; volatile oil; double flavonoids; tannins; anti-hair loss 侧柏(Platycladus orientalis)，柏科，又名柏树、扁柏、香柏。侧柏叶气微香，味苦涩、微辛，具有凉血止血、祛风降湿、化痰止咳、消肿散毒、乌亮须发的功效，在临床上常用于治疗出血症、风湿痹痛、高血压、咳喘烫伤等症。《本草汇言》：“侧柏叶，止流血，去风湿之药也。凡吐血、衄血、崩血、便血，血热流溢于经络者，捣汁服之立止；凡历节风痱周身走注，痛极不能转动者，煮汁饮之即定。惟热伤血分与风湿伤筋脉者，两病专司其用。但性味苦寒多燥，如血病系热极妄行者可用，如阴虚肺燥，因咳动血者勿用也。如痹病系风湿闭滞者可用，如肝肾两亏，血枯髓败者勿用也。” 1 侧柏叶化学成分研究 侧柏叶中的化学成分主要有挥发油、黄酮、鞣质等，现分述如下: 1. 1 挥发油 侧柏叶中含挥发油(CE)、同时蒸馏萃取法(SDE)和水蒸气蒸馏－萃取法(DSE)三种方法提取侧柏叶挥发性成分，采用气相色谱－质谱法(GC－MS)对挥发性成分进行分析。 酶提取法提取侧柏叶挥发油，鉴定出32 种化合物，占挥发油总量的98.73%，其主要成分为雪松烯，占挥发油总量的41.25%;同时蒸馏－萃取法提取侧柏叶挥发油，鉴定出29 种化合物，占挥发油总量的97.14%，其主要成分为雪松醇，占挥发油总量的39.06%;水蒸气蒸馏－萃取法提取侧柏叶挥发油，鉴定出32 种化合物，占挥发油总量的98.67%，其主要成分为雪松醇，占挥发油总量的31.43%[1]。用GC－MS分析侧柏叶挥发油成分，其主要成分为柏木脑( 30%)，还含有α－蒎烯( 5%)、3－蒈烯( 3%)、乙酸松油酯(4%)、异石竹烯(4%)、α－石竹烯(2%)、萜醇类(5% ～ 6%) 等化学成分[2]。用水蒸气蒸馏法从侧柏叶中提取挥发油，采用GC－MS对化学成分进行鉴定，共鉴定了33个成分，占挥发油总成分的80%以上[3]。用GC－MS 对侧柏叶、种皮和种子挥发油的化学