乳腺自由基代谢特点与乳牛酒精阳性乳发生的关系.pdfVIP

乳腺自由基代谢特点与乳牛酒精阳性乳发生的关系 王振勇，刘建柱，王林，王艳明，王鹏，王永 （山东农业大学动物科技学院，山东泰安 271018 ） 摘要：本文对奶牛乳清和血清中的各种抗氧化指标进行了检测，从自由基代谢的角度分析了乳腺的自由基代谢特点和 酒精阳性乳的发病机理。综合分析试验结果，乳腺组织本身抗氧化能力较差，但机体的保护性代偿能有效维持乳腺分 泌细胞的正常分泌；而阳性牛体内发生了过度的过氧化反应，机体总抗氧化能力下降，机体的抗氧化系统已不能有效 地清除活性氧及代谢产物，以至于过多的氧自由基对乳腺上皮分泌细胞细胞膜造成了严重损伤，从而引起乳腺细胞分 泌异常乳。 关键词：自由基代谢；酒精阳性乳；乳腺 Relationship Between the Free Radicals Metabolism in Mammary Gland and Alcohol Positive Milk * WangLin ，WangZhen-yong ，LiLong ，CaoAi-zhi，WangYan-ming ，WangPeng ，WangYong (Animal Science and Technology College ， Shandong Agricultural University ，Tai’an. Shandong，271018) Abstract ：Some anti-oxidative indexes in the whey and serum of cow were detected. The characteristic of / the free radicals metabolism in the mammary gland and the principle of alcohol positive milk(APM) / occurring were expounded in this paper from the angle of the free radicals metabolism. According to the result of experiment ，the ability of anti-oxidation of the mammary gland is worse than other tissues. But the protective compensation in the body can maintain the normal secretion of the epithelial cells of mammary gland effectively. But excessive anti-oxidative reaction occurs and the ability of total anti-oxidative goes down in the cow with APM. The system of anti-oxidation in the body can not eliminate the active oxygen and metabolites effectively，so that the surplus of free radicals do harm to the epithelial cells of mammary gland. It leads to the occurring of alcohol positive milk. Key words ：metabolism of free radicals ；alcohol positive milk ；mammary gland 低酸度酒精阳性乳（alcohol positive milk，简称APM ）是指乳酸度在11°T-18°T之间，用70% 中性 酒精与等量的新鲜牛奶混合，产生微细颗粒和絮状凝块的乳[1,2] 。与正常牛奶相比，这种乳热稳定性 较差，在 120℃以上时易发生凝固，造成加工设备