重症监护病房分离的常见病原菌流行状况及耐药性监测.pdfVIP

·12 · Modern Practical Medicine, Janury 2009, Vol. 21, No. 1 重症监护病房分离的常见病原菌流行情况及 耐药性监测 汪一萍，俞万钧 【摘要】 目的 调查医院重症监护病房 （ICU）分离的病原菌的流行情况及抗菌药物耐药性。 方法 对 ICU 分离的655 株院内感染病原菌的流行情况及其耐药性进行回顾性分析。 结果 655 株院内感染病原 菌中分离率前三位分别为铜绿假单胞菌、鲍氏不动杆菌和肺炎克雷伯肺炎亚种，其中非发酵占总分离菌的 ( ) 44.4%（291/655），革兰阴性需氧杆菌占27.0%（177/655），真菌占15.1% 99/655 , 革兰阳性球菌占9.2% ( ) 60/655 ；病原菌对抗菌药物多重耐药，泛耐药情况严重。 结论 ICU 病房病原菌构成及耐药性与普通病 房明显不同，应根据其病原学及抗菌药物耐药性合理选择抗菌药物。 【关键词】 加强医疗病房；交叉感染；微生物药物敏感试验 ( ) 【中图分类号】 R446.5 【文献标识码】 A 【文章编号】 1671-0800 2009 01-0012-04 Variation of clinical bacterial isolates and antibiotic resistance in Intensive care unit ( ) WANG Yiping,YU Wanjun. Ningbo Yinzhou People,s Hospital, Ningbo 315040,China 【 】 Abstract Objective To investigate changes in drug resistance and distribution of clinical isolates from the in- ( ) , tensive care unit ICU in Yizhou people s hospital. Methods We retrospectively analyzed the 655 strains from cli- nical samples in the ICU of our hospital in 2007. Results The dominant pathogens were pseudomonas aeruginosa ( ) ( ) ( ) 13% ,Acinetobacter baumanni 9.9% and klebsiella pneumoniae 9% .Non-fermentative bacteria accounted for ( ) ( ) ( ) 44.4% 291/265 ; gram-negenative aerobasilus accounted for 27.0% 177/655 ; fungi accounted for 15.1% 99/655 , ( ) and gram-positive cocci accounted for 9.2% 60/655 . Conclusion The pathogenic bacteria structure and drug re- sistance in intensive care unit are diferent from those in ordinary ward. So, it is very import