模拟失重条件下与选择心算联系的脑电位的动态变化.pdfVIP

第 11 卷 　第 3 期 　　　　　　　　　　航天医学与医学工程 　　　　　　　　　　　　Vol. 11 　No. 3 1998 年 　6 月 　　　　　　　　　Space Medicine Medical Engineering 　　　　　　　　　　J un. 1998 模拟失重条件下与选择心算关联的 脑电位的动态变化 赵　仑　魏金河　严拱东 陈文娟　段　然　任　维 摘要 　为研究模拟失重对脑功能状态的影响 ,在 15 名正常被试者中比较了头低位倾斜 ( ) ( ) - 10°HD T ,模拟失重 和头高位倾斜 + 20°HU T ,对照 条件下视觉选择心算的事件关 ( ) 联电位 ERPs ,在每种体位的 2 h 期间各进行 5 套测试。结果表明 :靶和非靶闪光信号 引起不同的正慢电位;靶信号的正慢电位时程和幅值显著长于和高于非靶信号 ,尤以后脑 区为最;与 HU T 比较,在 HD T 条件下正慢电位的幅值降低 ,且在第 4 及第 5 套记录时更 明显。提示模拟失重对高级脑功能有一定的影响。 关键词 　失重模拟 　选择心算 　事件关联电位 　头低位倾斜 　头高位倾斜 中国图书资料分类法分类号 　R852. 22 Changes of Brain Potentials Related to Selective Mental Arithmetic during Simulated Wei ghtlessness . ZHAO Lun , WEI Jinhe , YAN Gongdong , CHEN Wenjuan , DUAN Ran , REN Wei. Space Medicine Medical Engineering ,1998 ;11 (3) :167～171 Abstract 　To study the effect of simulated weightlessness on brain function state ,the brain event - related potentials ( ERPs) during a selective mental arithmetic task were compared between head down tilt ( HD T) and head up tilt ( HU T) in 15 normal subjects. The results were : target ( T) flash signals induced significant slow positive potentials and they decreased significantly in amplitude especially during HD T as compared with that during HU T. The data provide new evidence indicating that the ability of brain response declined during simu2 lated weightlessness. Key words 　weightlessness simulation 　selective mental arithmetic 　event - related poten2 tials 　head down tilt 　head up tilt Address reprint requests to 　ZHAO Lun. Institute of Space Medico - Engineering ,Beijin g 100094 ,China 　　目前 , 航天中脑功能的变化日益受到关 的。魏金河等[3 ,4 ]发现模拟失重对脑的注意功 注[1 ,2 ] ,