六味五灵片联合二甲双胍治疗脂肪肝 疗效观察.pdfVIP

58 ●临床研究● 《中国医学前沿杂志 （电子版）》2013 年第5 卷第12 期 六味五灵片联合二甲双胍治疗脂肪肝 疗效观察 杜彬 （山东省淄博市第四人民医院　内科，淄博　255000 ） 【摘要】目的　观察六味五灵片联合二甲双胍片治疗脂肪肝的临床疗效。方法　将 12 1 例脂肪肝患者 随机分为治疗组 （61 例）和对照组 （60 例）。治疗组口服六味五灵片和二甲双胍片，对照组只口服二 甲双胍片，疗程均为24 周，观察两组患者治疗前后的临床症状、肝功能及血脂水平。结果　治疗组 患者治疗后谷丙转氨酶 （ALT ）、谷氨酰转肽酶 （GGT ）下降幅度及血脂改善情况均明显优于对照组， P ＜0.05 ）。结论　六味五灵片联合二甲双胍能够明显改善脂肪肝患者的肝功能及血脂 差异有显著性 （ 状况，并且未见明显不良反应。 【关键词】脂肪肝；六味五灵片；盐酸二甲双胍片 The clinical observation of Metformin hydrochloride tablets combined with Liuweiwuling tablets on fatty liver DU Bin (Department of Internal Medicine, the Fourth Peoples Hospital of Zibo City, Shandong 255000, China.) Corresponding author: DU Bin, E-mail: guoguo818@ Abstract Objective To observe the clinical effect of Metformin hydrochloride tablets combined with 【 】 　 Liuweiwuling tablets on fatty liver disease. Methods　A total of 121 fatty liver patients were randomly divided into treatment group(61 cases) and control group(60 cases). The treatment group were treated with Liuweiwuling tablets and Metformin hydrochloride tablets; while the control group were only given Metformin hydrochloride tablets. The treatment are all for 24 weeks. At the meantime, observe the clinical symptoms, liver function and blood lipid levels. Results　After 24 weeks’ treatment, the descend range of ALT and GGT and the levels of TG and TC of the treatment group were greater than the control group, and the difference was statistically significant (P ＜ 0.05). Conclusions　The therapy of Liuweiwuling tablets combined with Metformin hydrochloride tablets could improve liver function and blood lipid levels for patients with fatty liver disease and there’s no obvious adverse reaction during the research. Key words Fatty liver; Liuweiwuling tablets; Metformin hydrochloride tablets 【 】 随着人们生活水平的提高，脂肪肝这一疾病在 1 　材料与方法 三高人群中的发病率逐年递增，且逐渐呈现低龄 1.1　一般资料　12 1 例脂肪