关于我院围手术期病人抗菌药物的应用分析.docVIP

关于我院围手术期病人抗菌药物的应用分析 摘要: 目的: 了解我院抗菌药物的使用现状, 分析围手术期抗感染用药情况,并作出客观评价。方法：根据事先设计好的调查表, 按统一的填表要求收集6个科室450例手术病人的出院病例, 依据《抗菌药物指导原则》对病例作回顾性调查分析。结果：450例手术患者中，432例使用抗菌药物，使用率95.97%;预防性用药325例，占72.27%；治疗性用药125例，占27.73%；无指征使用抗菌药物的有110例，占24.41%；据统计，450例使用抗菌药物的患者病人中，合理用药患者386例，占85.78%；基本合理的用药患者41例，占9.11%；不合理的用药患者23例，占5.11%；抗菌药物使用八大类共36种，使用率前三类的是：头孢类，硝基咪唑类，青霉素类。结论：本院外科围手术期应用抗菌药物存在不合理性,亟需根据《抗菌药物临床应用指导原则》进行规范化管理。 关键词：手术期间;抗菌药;抗生素预防; 应用分析 The applicable analysis of antibacterials in our hospital to the operational patients Abstract : Objective: To investigate the use of antibiotic in our hospital, and to analyze the application of antibiotic during perioperative period and make objective evaluation.Method: According to the designed table with unified contents and stand-ard,retrospective investigation was made in 450 operated patients who had been discharged from the hospital. Results: In 450 patients,432 cases use antibi -otic,usage is 95.97%;prophylactic medication 325 cases,accounting to 72.27%；remedial medication 125 cases, accounting to27.73%,no indicated to use antibiotic 110 cases,accounting to 24.41%;according to status,450 cases patients,reasonable to use antibiotic is 386 cases,accounting to 85.78%;the patients who are basic reasonable to use antibiotic 41 cases,accounting to 9.11%; the patients who are not reasonable to use antibiotic 23 cases,accounting to 5.11%;the usage of antibiotic is 8 kinds,together with 36 kinds,the first three kinds respectively is :Cephalo -sporin ,nitroimidazolean and penicillin.Conclusion : Irrational use of perio -perative antibacterial agents existed in this hospital.It is necessary to standardize administration of prophylactic antibacterial agents according to?Guideline on Clinical Use of antibacterials?. Key Words:intraoperative period ; antibacterial agents ; antibiotic prophylaxis ; applicable analysis 抗菌药物被广泛应用于临床，因此其使用的合理性与否对细菌耐药性的产生和发展具有重要的影响。合理使用抗菌药物的最基本原则是尽力做到安全、有效。随着近年来抗菌药物新品种的不断涌现及经济利益的影响，对抗菌药物的应用日益复杂，出现了抗菌药物的应用偏多偏滥以及细菌耐药性不断增加和不良反应等问题。围