SO杂稠三环化合物合成和生物活性研究.pdf

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ABSTRACT ofLomaliumSuksdo功,, SuksdorfinI,isolatedfrom thefruit bythePharmacy SchooloftheNorthCarolinaUniversityatChapelHillU.S.A, S a pyranocoumarm derivativewithinterestinganti-HIVactivity.Modificationofthiscompoundledto 5,whichdemonstratedextremelypotent seriesofanalogs,suchascompound2,3,4, inhibitoryactivityagainstHIVreplication.Researchshowsthatthesecompounds exerttheiranti-HIVactivitythroughmechanismsotherthaninhibitionofHIVRT, verylikelytobeef

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