心脏再同步治疗术后QRS时限缩短的预测因素分析.pdfVIP

中华临床医师杂志( 电子版)2013 年8 月第7 卷第15 期 Chin J Clinicians(Electronic Edition),August 1,2013,Vol.7,No.15 ·6941 · ·临床论著· 心脏再同步治疗术后 QRS 时限缩短的预测 因素分析 乔青 丁立刚 王靖 牛红霞 华伟 【摘要】 目的 寻找心脏再同步治疗术后QRS 时限缩短的独立预测因素。方法 根据术后QRS 时限 是否缩短，将80 例接受心脏再同步治疗的心力衰竭患者分为2 组。比较两组间的基线资料和左心室电极植 入理想靶静脉的比例，使用多变量Logistic 回归分析寻找术后QRS 时限缩短的独立预测因素，使用受试者 工作曲线评价有关变量对术后 QRS 时限缩短的预测能力。结果 术后 QRS 缩短组男性比例小（21/40 vs. 31/40，P ＝0.020 ），术前QRS 时限更长[ （186.3±24.9）ms vs. （157.0±26.9）ms ，P ＝0.000] 。Logistic 回归 分析显示性别（P ＝0.010，OR＝0.218 ）、术前QRS 时限（P ＝0.000，OR＝1.050）为术后QRS 时限缩短的 独立预测因素。受试者工作曲线显示术前QRS 时限≥170 ms 预测术后QRS 时限缩短的敏感性为0.750，特 异性为0.800 。结论 性别、术前QRS 时限为心脏再同步治疗术后QRS 时限缩短的独立预测因素，女性或 术前QRS 时限≥170 ms 的患者在心脏再同步治疗术后更多出现QRS 时限的缩短。 【关键词】 预测； 心脏再同步治疗； QRS 时限 Predictors of shortened QRS duration after cardiac resynchronization therapy QIAO Qing, DING Li-gang, WANG Jing, NIU Hong-xia, HUA Wei. Department of Cardiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing 210008,China Corresponding author: HUA Wei, Email: drhua@ 【Abstract 】 Objective To search independent predictors of shortened QRS duration after cardiac resynchronization therapy(CRT). Methods Eighty heart failure patients who received cardiac resynchronization therapy were divided into two groups according to whether the QRS duration was shortened after CRT implantation. The baseline parameters and ratio of ideal target vessel were compared between the two groups. Logistic regression was used to reveal the independent predictors of post-implant QRS duration shortening. Receiver Operative Characteristic (ROC) curve was employed to assess the predictive ability of related parameters. Results The