2-II细胞生物学的研究方法应用研究.pdf

细胞生物学研究方法 细胞形态结构的观察方法 细胞组分的分析方法 细胞培养、细胞工程 与显微操作技术 1 细胞形态结构的观察方法 光学显微镜技术 （Light Microscopy ） 电子显微镜技术 (Electro Microscopy) 扫描隧道显微镜 (Scanning Tunneling Microscope ) 扫描探针显微镜 （Scanning Probe Microscope） 2 History of the Microscope A long time ago (around the 1st century) someone picked up a piece of crystal which was thicker in the middle…looked through it and discovered it made things look LARGER. 3 History of the Microscope • That piece of crystal was called a “ magnifying glass” and then later was called a lens because it was shaped like a lentil seed. = 4 History of the Microscope • Then, in the 13th century (1200’s) an Italian inventor made the first eye glasses, allowing the wearer to have magnification. His name was Salvino D’Armate. Eye glasses were also called spectacles. 5 History of the Microscope • The earliest forms of magnification were magnifying glasses, usually between 6x to 10x,