1000 个有或无高血压的2 型糖尿病人中动脉僵硬度和HA1c 之间的关联.docVIP

{0Association of arterial stiffness with HbA1c in 1,000 type 2}100{ 1000个有或无高血压的2型糖尿病人中0}{0diabetic patients with or without hypertension}0{动脉僵硬度和HbA1c之间的关联0} {0Yuhong Chen ? Yun Huang ? Xiaoying Li ?}0{Yuhong Chen ? Yun Huang ? Xiaoying Li ?0} {0Min Xu ? Yufang Bi ? Yu Zhang ? Weiqiong Gu ?}0{Min Xu ? Yufang Bi ? Yu Zhang ? Weiqiong Gu ?0} {0Guang Ning}0{Guang Ning0} {0Abstract}0{摘要：0}{0The objective is to evaluate the association of}0{本项研究的目的0}{0arterial stiffness [brachial-ankle pulse wave velocity (ba- PWV)] with glycemic control and duration of type 2 diabetes in diabetic subjects with or without hypertension.}0{是在有或无2型糖尿病的对象中，评估动脉僵硬度[臂踝脉搏波速度（ba-PWV）]和血糖控制以及病龄之间的关联。0}{0One thousand Chinese diabetic patients (562 with hypertension, 438 without hypertension) were included in this study.}0{1000个中国糖尿病人（562人有高血压，438人无高血压）被纳入本项研究。0} {0All patients underwent ba-PWV and biochemical measure- ments.}0{所有病人都进行了ba-PWV测量和生化化验。0} {0Ba-PWV was significantly higher in diabetic subjects with hypertension than those without hypertension (1779 ±341 vs. 1691 ± 342 cm/s, P 0.0001), and these subjects were under similar glycemic control (6.9 ± 1.5 vs. 6.9 ± 1.3, P = 0.86).}0{有高血压的对象ba-PWV显著高于无高血压对象（1779 ±341 比 1691 ± 342 cm/s, P 0.0001），这些对象的血糖控制情况相似（6.9 ± 1.5 比 6.9 ± 1.3, P = 0.86）。0}{0In diabetic and hypertensive subjects, ba-PWV was positively associated with HbA1c (1715 ± 314 vs. 1851 ± 335 cm/s, in subjects with HbA1c 6.5% and with HbA1c 7.0%, respectively, P 0.0001), as well as duration of diabetes (1671 ± 342 vs. 1791 ± 313 vs. 1861 ± 338 cm/s, in subjects with duration of diabetes 5 years, 5–10 years, and10 years, respectively, P all 0.05).}0{在糖尿病和高血压病人中， ba-PWV 和 HbA1c 呈正相关（在 HbA1c 6.5% 和 HbA1c 7.0% 的对象中,分别为 1715 ± 314 和 1851 ± 335 cm/s，P 0.0001）, 也和糖尿病病龄呈正相关（在病龄5年、5-10年和≥10 年的对象中，分别为 1671 ± 342、1791 ± 313、1861 ± 338 cm/s，所有P 0.05）。0} {0In diabetic subjects without hypertension, ba-PWV was not associated with HbA1c