林木比较基因组学研究进展.pdfVIP

HEREDITAS (Beijing) 2007 10 , 29(10): 1199―1206 ISSN 0253-9772 综述 DOI: 10.1360/yc-007-1199 1,2 1 1 1 王源秀 , 徐立安 , 黄敏仁 , 许远 1. , , 210037; 2. , 241000 : 比较基因组学是基因组学研究的重要内容。比较基因组学研究结果表明, 有可能将近缘种统一起来建立 超越物种界限的大遗传系统, 这对于林木而言具有更重要的意义。有关林木比较基因组学研究主要集中在杨柳 科、松科、蔷薇科、壳斗科和金缕梅科的一些树种中。研究发现林木近缘种基因组中存在广泛的共线性或同线 性及微共线性, 在进化过程中呈现高度保守性; 通过双向比对发现: 杨树和拟南芥基因组中有 13 019 对同源基 因的序列一致性平均达 93%, 其中 11 654 对同源基因的序列一致性超过基因长度的 90% 。文章概述了林木比较 基因组学研究的进展状况, 探讨了该领域的发展趋势, 以期为我国林木基因组学研究提供有益的参考。 : 林木; 比较基因组学; 共线性或同线性; 微共线性 Progress in research on forest tree comparative genomics 1, 2 1 1 1 WANG Yuan-Xiu , XU Li-An , HUANG Min-Ren , XU Yuan 1. Key Laboratory of Forest Genetics and Gene Engineering, Nanjing Forestry University , Nanjing 210037, China ; 2. Anhui Normal University, Anhui Wuhu 241000, China Abstract: Comparative genomics is one of the important research fields in genomics. By comparative genomic studies it was possible to establish a giant genetic system beyond one species which might be significant to tree. Comparative ge- nomics in Salicaceae, Pinaceae, Rosaceae, Fagaceae and Hamamelidaceae had shown that the organization of genomes remained highly conserved over long evolutionary periods and extensive synteny or collinarity or microcollinarity existed in tree genomes. A total of 13 019 pairs of orthologs were identified between genes in Populus and Arabidopsis using the best bidirectional Basic Local Alignment Search Tool (BLAST) hits, with an average mutual coverage of these alignments equal to 93%; 11 654 pairs of orthologs had greater than 90% alignment of gene lengths. The progress of comparative genomics