气相色谱-串联质谱法(GC-MSMS)测定塑料食品包装材料中的全 .docVIP

气相色谱-串联质谱法(GC-MS/MS)测定不粘锅涂层中的全氟辛酸 吴晓红1，周宇艳，y=14.589x-0.1861；方法检出限为0.001mg/kg；平均回收率为82.7%～90.6%；相对标准偏差（n=6）为5.6%～6.9%。该方法简便、快速、抗干扰能力强、重复性好，可用于不粘锅涂层中全氟辛酸的快速分析。 关键词：气相色谱-串联质谱；不粘锅涂层；全氟辛酸 Determination of perfluooctanoic acid(PFOA) in the coating layer of nonstick pan by gas chromatography-tandem mass spectrometry Wu Xiao-hong1, Zhou Yu-yan1, Ma Ming1, Sun Ming-xing1, Chenqian2 (1.Technical Center for Industrial Products and Raw Materials Inspection, Shanghai Entry-Exit Inspection and Quarantine Bureau, Shanghai Pudong 200135；2. Donghua University, Shanghai Changning 200051) Abstract:The method for the determination of PFOA in the coating layer of nonstick pan was developed by gas chromatography-tandem mass spectrometry (GC-MS/MS). The sample was extracted with methanol by accelerated solvent extraction, and then the extract was quantified after derivation by GC-MS/MS method using perfluorodecanoic acid methyl ester as an internal standard. The results showed the linear range of the instrument was 0.0020mg/L～5.0mg/L with the linear equation of y=14.589x-0.1861 and correlation coefficient of 0.9999 and the method lowest detection limit was 0.001mg/kg. The recovery rates were 82.7%～90.6% and relative standard deviation (RSD) (n=6) values were 5.6%～6.9%. This method is simple and rapid, and has strong anti-interference capability and good repeatability, which is applicable to the analysis of PFOA in coating layer of nonstick pan. Keywords: GC-MS/MS; coating layer of nonstick pan; PFOA ___________________________________________________________________________ 收稿日期：2013年1月4日；修订日期：2013年8月26日 基金项目:食品接触材料中敏感物质迁移模型研究及预测评估(2011IK041)；质检公益性行业科研专项（2012104020）资助 作者简介:吴晓红（1964-），女，汉族，上海人，上海出入境检验检疫局，高级工程师。E-mail: maming@shciq.gov.cn 全氟辛酸（PFOA）是一种人工合成的化学品,广泛应用于油库、机场、军事设施等场所的消防材料中，也是氟塑料、氟橡胶和有机氟织物整理剂等生产过程中不可缺少的原料[1]。PFOA是具有中等毒性的肝致癌物，可增加人类患癌的风险，由于其化学惰性及其广泛的生产及使用，已造成严重的环境累积及污染[1]。当前，一些食品接触材料中会使用含氟聚合物，较常见的如不粘锅的含氟涂层，其具有独特的耐热、耐低温、自润滑及化学稳定性等特点[2]。其中可能会残留一定的PFOA，若人们使用这些产品便会对人体健康造成危害，因此，需建立有效方