冠状动脉支架置入术后患者对抗血小板治疗依从性及其对预后影响.pdf

·334· 冠状动脉支架置入术后患’者对抗血小板 治疗的依从性及其对预后的影响 朱中玉1 陈岩1 高传玉1 牛振民1 黄克钧1 李牧蔚1 [摘要] 目的：了解冠状动脉支架置入术后患者对抗血小板治疗的依从性及其对临床预后的影响。方法：对 504例行冠状动脉内支架置入术的患者进行临床随访，调查抗血小板药物的应用情况及主要不良心脏事件 (6．55％)患者未服用阿司匹林；30例(5．95％)停止所有的抗血小板治疗。完全停止抗血小板治疗使非致死性心 9．77，95％CI 肌梗死(MI)(10．00％；1．05％，OR 3．25，95％CI 15．35，95％CI OR3．21，95％CI1．19～8．65，P 依然存在(非致死性MI，OR 2．02～78．06，Po．01；MACE 0．05)。结论：冠状动脉支架置入术后患者对抗血小板治疗的依从性良好，完全停止抗血小板治疗会增加非致死 性M1及MACE的危险。 [关键词]血管成形术，经腔，经皮冠状动脉；抗血小板治疗；依从性；预后 [中图分类号]R654．3[文献标志码]A [文章编号]1001—1439(2009)05—0334-04 withdual anditsinfluenceonclinical Complianceantiplatelettherapy outcomesin patientsundergoingpercutaneouscoronarystenting ZHU CHENYanGAO HU．ANG LIMuwei Zhongyu ChuanyuN儿，Zhengmin Kej“，z of Provincial Cardiology，HenanPeople (Department Abstract the withdual anditsinfluenceonclinical Objective：Toinvestigatecompliance antiplatelettherapy outcomesin was in504 patientsundergoingpercutaneouscoronarystenting．Method：Thefollow-upperformedpa— tients inour thedurationand of and undergoingcoronarystentingdepartment，includingdosageaspirin clopidogrel and adversecardiacevents(MACE)．Result：Thewas21．19months．At major averagefollow-up discharge，498 on durationof patients(98．8％)wereaspirintherapy，503patients(99．8％)tookclopidogrel，theclopidogrel was(9．56土3．95)months．At tO advice。64