类风湿性关节炎基础研究及进展.pptVIP

CIA大鼠的骨保护作用-MRI Refer：Fang Du,liang-jing Lv,et al. T-614,a novel immunomodulator,attenuates inflammation and articular damage in collagen induced arthritis. Arthritis Research Therapy 2008,10:R136 a: normal rats; b: CIA rats treated with vehicle; c: CIA rats treated with MTX; d:CIA rats treated with nimesulide e/f: CIA rats treated with T614; g: CIA rats treated with T-614 and MTX a b c d e f g soft tissue swelling (yellow arrow) and localization of bone marrow edema (yellow triangle) MRI检测结果：艾得辛能够几乎完全抑制CIA的炎症和骨髓内水肿。 影像学评估 –X线和CT T-614 offered significant protection against joint dam