早产相关危险因素的调查分析.pdfVIP

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维普资讯 · 7O· 中国优生与遗传杂志2008年第 16卷第5期 早产相关危险因素的调查分析 张高峰 ,王志萍 ,林大枫 ,张 媛 (1.济南铁路疾病预防控制中心 (所)劳动卫生与环境卫生室,山东 济南 250001; 2.山东大学公共卫生学院流行病与卫生统计学研究所,山东 济南 250012) 摘 要:目的 探讨怀孕季节是否是早产的危险因素。方法 采用成组病例对照研究,用卡方检验和单因素 logistic回 归分析的方法对可疑有季节性变化的危险因素进行单因素分析;再对筛选出的危险因素进行多因素非条件 logistic回归分 析,筛选出早产主要危险因素。结果 经单因素分析,得到7项可疑早产危险因素,分别是:怀孕季节、经期天数、孕前 收缩压、孕前舒张压、分娩前收缩压、分娩前舒张压、新生儿体重。经进一步多因素 logistic回归分析发现:怀孕季节和经 期天数是早产的危险因素。结论 怀孕季节和经期天数是早产的危险因素。 关键词 :早产;怀孕季节;logistic回归分析;病例对照研究 中图分类号:R714.21 文献标识码:B 文章编号:1006—9534 (2008)05—0070—03 Thesurveyanalysisofriskfactorsforprematuredelivery.ZhANGGao-feng,WANGZhi-ping,UNDa-feng ,ZHANG Yuan.(1.TheSectionOOZeofOccupatoinalHealthandEnvironmentalHealth,JinanRailwayCenterforDiseaseControlandPreven- toin,JinanShandong 250001China;2.InstituteofEpidemiologyandHealthStatistics,SchoolofPublicHealth,Shandong University , JinanShandong 250012hC ina) Abstract:Objective:Toinvestigateifseasonofpregnancyistheriskfactorofprematuredelivery.Method-Afterthesuspected factorswereanalyzedbyChi—squaretestnadmono—logisticregression.sevenriskfactorsforprematurewere revealed.Thenwi出 a multiplelogisticrergession,weobtainedtheprimaryriskfactorsforprematureandcalculatedtheetiologicalfractionofeachriskfactor. Results:Singlefactorstatus,Sevenriskfactorsforprematureweretimeofpregnnacy,periodofmenstrual flow,theprogravidsystolic pressure,theprograviddiastolicpressure,prepartalsystolicpressure,prepartaldiastolicpressure,neonatalweight.Bythemultiplelo- gisticregressionmodelwefoundthefollowingfactorsthatareindependentlycorrelatedwithhteoccurrenceofpretermdelivery:season ofprengnacy.period ofmenstrual flow.Conclusion:Thefollow factorsmaybethepreterm delivery riskfactors.Suchas:seasonof prengnacy,period ofmenstrual flow. Keywords:Prematuredelivery;Seasonofprengnacy;Logisticnaalysis;Acase—controlst

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