彭林-剖宫产麻醉前预注_-二磷酸果糖对新生儿影响的研究--..docVIP

剖宫产麻醉前预注1,6-二磷酸果糖对新生儿影响的研究 广东省东莞市大岭山医院麻醉科 彭林 王仕红 李云龙 邮编523820 【摘要】目的 探讨剖宫产麻醉前预注1,6-二磷酸果糖对新生儿的影响。方法 随机选取2009年1月～2010年1月在我院住院行剖宫产的120例产妇作为研究对象，随机分为研究组和对照组，每组各60例。研究组在麻醉前预注1,6-二磷酸果糖；对照组在麻醉前预注等剂量生理盐水。结果 胎儿娩出时及出生后1 min Apgar评分组和比较有统计学意义P＜0.05出生后5 min和0 min Apgar评分组和比较无统计学意义组 PO2和H较对照组偏高，PCO2较组偏低有统计学意义P＜0.05结论 剖宫产麻醉静脉注射1,6-二磷酸果糖是一种行之有效的提高剖宫产手术新生儿安全性的方法，值得在临床推广应用。 【关键词】1,6-二磷酸果糖；剖宫产；腰硬联合麻醉omparising the effects of FDP pre- intravenous injection on neonatal before the CSEA in cesarean section Peng Lin Wang Shi Hong Li Yun Long county Zip code 523820 【Abstract】Objective To detected influence of 1,6 – diphosphate pre-anesthesia injection before cesarean section the on newborns. Methods Randomly selected 120 patients from January 2009 to January 2010 in our hospital did cesarean section maternal as the research object, the control group were randomly divided into groups, each group each 60 cases. Study group before the pre-anesthesia injection of 1, 6 - diphosphate; the control group before anesthesia and other pre-saline injection. Results After birth when the baby is delivered, and 1 min Apgar score between study group and control group, the difference was statistically significant (P＜0.05). 5 min and 10 min Apgar score between study group and control group, the difference was not statistically significant (P＞0.05). PaO2 and pH of the study group were higher than the control group, PaCO2 of the study group was lower than the control group, the difference was statistically significant (P＜0.05). Conclusion Intravenous anesthesia cesarean section 1,6 - diphosphate is effective to improve the safety of cesarean section newborn, it is worth in the clinical application. 【Keywords】FDP；Cesarean section；Epidural anesthesia 随着社会的发展以及多种原因，越来越多的产妇选择剖宫产。腰硬联合麻醉Combined spinal epidural anesthesia，CSEA作为一种联合麻醉方法已成为剖宫产手术的常规的麻醉方法产妇于CSEA后低血压的发生率严重的低血压减少子宫胎盘的血液灌注造成宫内胎儿缺血缺氧性损伤[4,5]将不可避免地引起新生儿的酸血症及心肌损伤如何充分利用CSEA的优点使胎儿以最佳的状态娩出一直是麻醉医师所关注的课题。1,6-二磷酸果糖（Fructose DiphosphateFDP）是细