脂炎消治疗脂肪肝例的临床报告文章--程井军.docVIP

脂炎消治疗脂肪肝的临床 1湖北中医药大学附属专家门诊部（430061） 2深圳市东湖医院中西医结合肝病科（508020） 　摘要　目的:探讨脂炎消对脂肪肝的临床疗效。方法:选择脂肪肝患者100例,随机分为治疗组50例和对照组50例,治疗组口服脂炎消,对照组服用熊去氧胆酸胶囊,观察两组治疗后的总有效率、肝功能及血脂的变化。结果:经治疗后治疗组总有效率优于对照组(P0.05);患者丙氨酸氨基转移酶(ALT)、天门冬酸氨基转移酶(AST)和谷氨酰转肽酶(GGT)均明显降低,且优于对照组(P0.05或0.01);同时总胆固醇(TC)、甘油三酯(TG)及低密度脂蛋白(LDL)较治疗前显著降低(P0.05或0.01),其中TG与对照组比较差异有显著性意义(P0.05)，HDL较治疗前明显升高（P0.05）。结论:脂炎消治疗脂肪肝疗效显著,能明显改善肝功能,降低血脂。　 　 关键词　脂肪肝;　脂炎消; 中医药 A Clinical Research on the Therapeutical Effectof QuzhiFugan Decoction on 50 Cases with Fatty Liver Cheng Jingjun 1 Peng Rui 1 Wu Qikai 2 1 Hubei College of Traditional Chinese Medicine （Wuhan， 430061） 2 Shenzhen Donghu Hospital (Shenzhen, 508020) Abstract Aim: To evaluate the clinical therapeutical effects of the Zhi－Yanxiao Decoction on fatty liver. Methods: 100 cases with fatty liver were divided into two groups randomly, the treatment group（ 50 cases）were treated with Shanzha Beimu Decoction, the Control group（ 50cases）were treated with Ursodeoxyside capsule. After treatment, the total efficiency rate, the markers of liver function and the levels of blood lipid were detected. Results: The total efficiency rate of the treatment group was better than that of the control group (P0.05). ALT, AST and GGT were significantly lowered than those of the control group (P0.05 or 0.01). Meanwhile, the level of TCh、TG and LDL were lowered markedly after treatment (P0.05 or 0.01). There was significant differences on TCh and TG between the two groups (P0.05). Conclusion: The curative effect of Zhi－Yanxiao Decoction was markedly effective on fatty liver. It can regulate liver functions and decrease blood lipid obviously. Keywords Fatty Liver Zhi－Yanxiao Decoction Traditional Chinese Medicine 　 非酒精性脂肪性肝炎（Nonalcoholic Steatohepatitis, NASH）由单纯性脂肪肝发展而来，如不治或治疗不当，在氧自由基、细胞因子及脂质过氧化等多种因素作用下可转化为脂肪性肝纤维化和肝硬化［1］。但因其发病机理未完全明了，尚无治疗的特效药。中医药防治脂肪肝有其独特的优势，我们按照传统的中医理论，以健脾补肾、祛湿化痰、行气活血为治法，自拟脂炎消煎剂，在临床上取得满意疗效,现报告如下。 1　资料与方法 1.1　一般资料 100例脂肪肝患者均系东湖医院中西医结合肝病科2003年4月～