87例慢性化脓性骨髓炎病原菌构成及药敏分析.pdfVIP

物骨科材料 与临床研究 2012 06 月 ORT HO PA EDIC BIO MECHA NICS MAT ERIA LS AND C LINICAL ST UDY 第9 卷 第3 期 章编号： 著·实验研究 87 例 慢 性 化 脓 性骨 髓 炎 病 原 菌 构 成 及 药 敏 分析 陈爱宝 龚琦 宋建辉 曾国庆 [ ] 摘要 目的分析87 例慢性化脓性骨髓炎的病原菌菌种构成、药敏实验结果。方法 取慢性化脓性骨髓炎患者窦 道深部分泌物或病灶组织做细菌培养及药敏试验。结果 共培养出病原菌 120 株，感染率由高到低前三位菌为金 黄色葡萄球菌﹙占30% ﹚、铜绿假单胞菌﹙占25% ﹚、大肠埃希菌﹙占14.2% ﹚。万古霉素、亚胺培南是敏感率最 高药物。结 慢性化脓性骨髓炎的病原菌构成以金黄色葡萄球菌、铜绿假单胞菌为主，药敏试验是选用抗菌药 物的重要依据。 [ ] 关键词 骨髓炎；抗菌药物；药物敏感性 [ ] [ ] 中图分类号 R681.2 文献标识码 B Chen Aibao, Gong Qi, Song J ianhui, et al. Dep artment of orthopaedics , the No 425 Hosp ital of PLA, Sanya Hainan, 572008, China. [Abstract] Objective To analyse constitutes strains of pathogenic bacteria and drug sensitivity test of 87 cases of chronic suppurative osteomyelitis. Methods Bacteria culture and drug sensitive test were performed by taking sinus secretions or tissue in deep focus of infection from patients with chronic suppurative osteomyelitis. Results A total of 120 strains of pathogenic bacteria were isolated. From high to low infection rate the top 3 bacteria as Staphylococcus aureus ﹙30% ﹚, Pseudomonas aeruginosa ﹙25% ﹚, Escherichia coli ﹙14.2% ﹚. Vancomycin, imipenem were the highest rate of sensitive drug. Conclusion The main pathogens of chronic suppurative osteomyelitis were composed with Staphylococcus aureus, Pseudomonas aeruginosa. Drug sensitive test is the important basis for selection of antibiotics. [Key words] Osteo