糖尿病感染患者的病原菌分布及耐药性分析.pdfVIP

1118 Chinese Journal of Medicinal Guide 2013 Volume 15 No.7 (Serial No.117) 糖尿病感染患者的病原菌分布及耐药性分析 常青 (北京市丰台区铁营医院内科,北京100079) 【摘要】目的:分析内分泌科糖尿病(DM)感染患者常见病原菌的分布及耐药谱的变化,指导内分泌科合理用药。方法: 收集DM感 染患者标本,分离病原菌,分析各类标本分离的病原菌构成比;进行鉴定和药敏试验,对常用抗生素进行耐药性分析。结果:分离出329 株病原菌,主要来源于尿液、伤口分泌物、全血。分离出常见病原菌为大肠埃希菌、金黄色葡萄球菌、肺炎克雷伯菌、铜绿假单 胞菌、奇异变形杆菌、粪肠球菌、真菌。耐药率:大肠埃希菌、肺炎克雷伯菌、奇异变形杆菌对常用抗菌药物耐药率较低,大肠埃 希菌对氨苄西林的耐药率较高,肺炎克雷伯菌对氨苄西林的完全耐药,奇异变形杆菌对呋喃妥因、复方新诺明、氨苄西林的耐药率 分别为72.22% 、55.56%、50.00%;铜绿假单胞菌对头孢曲松、头孢唑啉的耐药率均为90% 。未发现耐万古霉素G+球菌,金黄色葡萄 球菌对青霉素的耐药率为94.29%,粪肠球菌对四环素,克林霉素,红霉素,喹努普汀/达福普汀的耐药率均大于86.67%。结论:通过细菌 耐药检测,可指导临床合理使用抗菌药物,为抗感染治疗提供依据。 【关键词】糖尿病;病原菌;药物敏感性试验;耐药性 R446.5 文献标识码】A 【文章编号】1009-0959(2013)07-1118-03 【中图分类号】 【 Analysis of Distribution and Drug-resistance of Common Pathogens in Diabetic Infection Patients Chang Qing (Beijing Fengtai Tieying Hospital, Beijing 100079, China) 【 】 To Analyse endocrinology diabetes(DM) patients infected with distribution of common pathogens and ABSTRACT Objective: resistance patterns of change, guidance Endocrinology rational drug use.Methods: DM-infected patients collected specimens, Pathogens, analyzing various specimens pathogens isolated constituent ratio; identification and susceptibility testing, resistance to commonly used antibiotics for analysis.Results: Isolated 329 pathogens, mainly from urine, wound secretions, whole blood. Common pathogens isolated were Escherichia coli, Staphylococcus aureus, Klebsiella pneumoniae, Pseudomonas aeruginosa, Proteus mirabilis, Enterococcus faecalis,