戊乙奎醚、东莨菪碱和阿托品用于老年患者术前用药的比较.pdfVIP

!逝压盛醒堂盘查2111笙!!月筮!!鲞箜!!翅』gi!垒!墅!堕!!趔：堕!!堡坠!!；!!!!y!!：!!!丛竺：!； ．临床研究． 戊乙奎醚、东莨菪碱和阿托品用于老年患者术前 用药的比较 疏树华潘建辉王瑞明 方才 【摘要】 目的 比较术前抗胆碱药用于老年患者的l临床效果。方法 45例择期需要全麻且年 min分别肌注戊乙奎醚0．01mg／kg、 龄≥65岁的老年手术患者，随机均分成A、B、C三组，麻醉前30 东茛菪碱0．3mg或阿托品0．5mg。记录用药前、用药后lo、20、30rain、气管插管后1rain各时点 SBP、DBP、HR、S1)()2等指标，并用VAS评分评定患者口干程度。结果A组用药后SBP、DBP较用 药前有下降趋势、HR减慢。气管插管后上述指标稍有上升；B、C组用药后30rain及气管插管后1 A组(Po．01)。注药后三组患者VAS口干评分均明显升高(Po．01)。结论戊乙奎醚比东茛 菪碱和阿托品更适合用于老年患者术前用药。 【关键词】 戊乙奎醚；东茛菪碱；阿托品；术前用药；老年 of and as inthe SHUShu—hua， Comparisonpenehyclidine，scopolamineatropinepremedieationselderly PANJian-hui，WANG Provincial Rui—ruing，eta1．DepartmentolAnesthesiology，Alfiliated Medical 230001，China Hospitaf。AnhuiUniversity，Hefei To theclinicaleffectsof and compare atropine [Abstract]Objective penehyclidine，scopolamine as inthe old premedicationselderly．MethodsForty-fivepatientsaged≥65yearsundergoingsurgery and anesthesiawere dividedintothree ofA。BandC，whowere general randomly groups given intramuscularof 0．01 0．3 and 0．5mg， injectionpenehyclidinemg／kg。scopolaminemg atropine 30minbefore and wererecordedbefore respectively，at anesthesia．SBP，DBP。HRSp()2 iniection。at 10。20．30minafter andat1minafter ofthirstwereevaluatedVAS inj’ection intubation．Degrees by aswell．ResultsSBP，DBPandHRweredecreasedafter in A，whichwere scoring slightlyinjectiongroup min inlectionandlmin increasedin ofBandCafter at30 after afterintubation(PO．05)． groups iniection SBP．I)BPandH