雌激素受体在肿瘤中的生物学作用.pdfVIP

现代肿瘤医学 2012 年 3 月 第 20 卷第 3 期 MODERN ONCOLOGY ，Mar. 2012 ，VOI. 20 ，NO. 03 ·625 · 雌激素受体在肿瘤 中的生物学作用 ， 王雪莹 王瑞安 The biological role of estrogen receptors in cancer WANG Xueying ，WANG Ruian Xij ing Hosp ital The Fourth Military Medical University ，Shaanxi Xi＇an 7 10032 ，China． 【Abstract 】The estrogen is mediated by estrogen receptors ( ERα and ERβ) ，which are steroid hormone receptors that modulate the transcription of target genes when bound to ligand． The activity of these transcription factors is regulated by a variety of facto