生物化学 Proteinsynthesis课件.pptVIP

Chapter 13 Proteinsynthesis what the translation needs 13.1 The genetic code 遗传密码 mRNA 分子中所储存的遗传信息是由其分子的四种碱基以特定顺序排列成的三个一组的三联体代表的，每种氨基酸都有其特定的三联体密码。 13.2 Transfer RNA 13.3 Ribosomes 13.4 Process of translation Principle for DNA replication: base-pairing Principle for protein synthesis: anticodon-codon base-pairing （反密码子－密码子） Initiation step The small subunit (30S) binds to the mRNA The initiator tRNA charged with N-formylmethionine (fMet-tRNA) binds to form the 30S initiation complex (30S起始复合物) The large ribosomal subunit binds to form a 70s initiation complex (70S起始复合物) with the hydrolys